Serveur d'exploration sur la grippe en Espagne

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Effectiveness of seasonal 2008-2009, 2009-2010 and pandemic vaccines, to prevent influenza hospitalizations during the autumn 2009 influenza pandemic wave in Castellón, Spain. A test-negative, hospital-based, case-control study.

Identifieur interne : 000485 ( Main/Exploration ); précédent : 000484; suivant : 000486

Effectiveness of seasonal 2008-2009, 2009-2010 and pandemic vaccines, to prevent influenza hospitalizations during the autumn 2009 influenza pandemic wave in Castellón, Spain. A test-negative, hospital-based, case-control study.

Auteurs : Joan Puig-Barberà [Espagne] ; Alberto Arnedo-Pena ; Francisco Pardo-Serrano ; María Dolores Tirado-Balaguer ; Silvia Pérez-Vilar ; Ester Silvestre-Silvestre ; Consuelo Calvo-Mas ; Lourdes Safont-Adsuara ; Montserrat Ruiz-García

Source :

RBID : pubmed:20875486

Descripteurs français

English descriptors

Abstract

We estimate the impact of the two previous influenza seasonal vaccines and the pandemic vaccine on risk of A (H1N1) 2009 laboratory confirmed hospitalizations during the autumn 2009 pandemic wave in Castellón, Spain. We conducted a test-negative, hospital-based, case-control study. Influenza A (H1N1) 2009 infection was detected in 147 (44%) of 334 patients hospitalized for a presumptive influenza related illness. No effect was observed for the 2008-2009 and 2009-2010 seasonal influenza vaccines. However, the pandemic vaccine was associated with an adjusted vaccine effectiveness of 90% (95% CI, 48-100%). Pandemic vaccines were effective in preventing pandemic influenza associated hospitalizations.

DOI: 10.1016/j.vaccine.2010.09.042
PubMed: 20875486


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">We estimate the impact of the two previous influenza seasonal vaccines and the pandemic vaccine on risk of A (H1N1) 2009 laboratory confirmed hospitalizations during the autumn 2009 pandemic wave in Castellón, Spain. We conducted a test-negative, hospital-based, case-control study. Influenza A (H1N1) 2009 infection was detected in 147 (44%) of 334 patients hospitalized for a presumptive influenza related illness. No effect was observed for the 2008-2009 and 2009-2010 seasonal influenza vaccines. However, the pandemic vaccine was associated with an adjusted vaccine effectiveness of 90% (95% CI, 48-100%). Pandemic vaccines were effective in preventing pandemic influenza associated hospitalizations.</div>
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<Year>2010</Year>
<Month>9</Month>
<Day>30</Day>
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<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline">
<Year>2011</Year>
<Month>1</Month>
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<PublicationStatus>ppublish</PublicationStatus>
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<ArticleId IdType="pii">S0264-410X(10)01352-6</ArticleId>
<ArticleId IdType="doi">10.1016/j.vaccine.2010.09.042</ArticleId>
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<li>Espagne</li>
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<region>
<li>Communauté valencienne</li>
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</list>
<tree>
<noCountry>
<name sortKey="Arnedo Pena, Alberto" sort="Arnedo Pena, Alberto" uniqKey="Arnedo Pena A" first="Alberto" last="Arnedo-Pena">Alberto Arnedo-Pena</name>
<name sortKey="Calvo Mas, Consuelo" sort="Calvo Mas, Consuelo" uniqKey="Calvo Mas C" first="Consuelo" last="Calvo-Mas">Consuelo Calvo-Mas</name>
<name sortKey="Pardo Serrano, Francisco" sort="Pardo Serrano, Francisco" uniqKey="Pardo Serrano F" first="Francisco" last="Pardo-Serrano">Francisco Pardo-Serrano</name>
<name sortKey="Perez Vilar, Silvia" sort="Perez Vilar, Silvia" uniqKey="Perez Vilar S" first="Silvia" last="Pérez-Vilar">Silvia Pérez-Vilar</name>
<name sortKey="Ruiz Garcia, Montserrat" sort="Ruiz Garcia, Montserrat" uniqKey="Ruiz Garcia M" first="Montserrat" last="Ruiz-García">Montserrat Ruiz-García</name>
<name sortKey="Safont Adsuara, Lourdes" sort="Safont Adsuara, Lourdes" uniqKey="Safont Adsuara L" first="Lourdes" last="Safont-Adsuara">Lourdes Safont-Adsuara</name>
<name sortKey="Silvestre Silvestre, Ester" sort="Silvestre Silvestre, Ester" uniqKey="Silvestre Silvestre E" first="Ester" last="Silvestre-Silvestre">Ester Silvestre-Silvestre</name>
<name sortKey="Tirado Balaguer, Maria Dolores" sort="Tirado Balaguer, Maria Dolores" uniqKey="Tirado Balaguer M" first="María Dolores" last="Tirado-Balaguer">María Dolores Tirado-Balaguer</name>
</noCountry>
<country name="Espagne">
<region name="Communauté valencienne">
<name sortKey="Puig Barbera, Joan" sort="Puig Barbera, Joan" uniqKey="Puig Barbera J" first="Joan" last="Puig-Barberà">Joan Puig-Barberà</name>
</region>
</country>
</tree>
</affiliations>
</record>

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